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이경해 ( Lee Kyung-Hae ) - 연세의료원
신경민 ( Shin Kyung-Min ) - 연세의료원
이현정 ( Lee Hyeon-Jeong ) - 연세의료원
김소영 ( Kim So-Young ) - 연세의료원
채정원 ( Chae Jung-Won ) - 연세의료원
김미라 ( Kim Mi-Ra ) - 연세의료원
한민영 ( Han Min-Young ) - 연세의료원
안미숙 ( Ahn Mi-Sook ) - 연세의료원
박진경 ( Park Jin-Kyung ) - 연세의료원
정미애 ( Chung Mi-Ae ) - 연세의료원
추상희 ( Chu Sang-Hui ) - 연세대학교 간호대학
황정화 ( Hwang Jung-Hwa ) - 연세의료원
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Abstract
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Purpose: This study was to develop evidence-based clinical practice guideline in order to prevent contrastinduced
nephropathy (CIN) for patients undergoing percutaneous coronary intervention (PCI).
Methods: The guideline was developed based on the "Scottish Intercollegiate Guidelines Network (SIGN)". The first draft of
guideline was developed through 5 stages and evaluated by 10 experts.(1) Clinical questions were ensured in PICO format.(2) Two researchers conducted a systematic search through electronic database, identifying 170 studies. We selected 27 full text articles including 16 randomized clinical trials, 7 systematic reviews, and 4 guidelines. Quality of each studies were evaluated by the Cochran’s Risk of Bias, AMSTAR, K-AGREEII. Among the studies, 11 studies were excluded.(3) The strength of recommendations were classified and quality of recommendations were ranked.(4) Guideline draft was finalized.(5) Content-validation was conducted by an expert group. All contents were ranked above 0.8 in CVI.
Results: Evidence-based clinical practice guideline to prevent CIN was dveloped.(1) The guideline for preventing CIN recommends using 0.9% saline.(2) Standardized rate of fluid therapy is 1 to 1.5ml/kg/hr.(3) Execute hydration for 6~12hrs before PCI and after PCI.
Conclusion: This study suggests evidence-based clinical practice guideline for preventing CIN which can be more efficiently used in clinical practice.
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KeyWords
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Contrast Media, Acute Kidney Injury, Evidence-Based Practice, Fluid Therapy
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원문 및 링크아웃 정보
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등재저널 정보
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